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But growing evidence supports that at least someforms of depression may also be linked to ongoing low-grade inflammation in the body. Previous studies have linked depression with higher level of inflammatory markers compared to people who are not depressed. When people are given proinflammatory cytokines, people experience more symptoms of depression and anxiety. Chronically higher levels of inflammation due to medical illnesses are also associated with higher rates of depression. Even brain imaging ofpeople with depression show that their brain scans have increased neuroinflammation . When your body is in an inflammatory state fighting off the common cold or flu, you canexperiencesymptoms overlapping withdepression disrupted sleep , depressed mood, fatigue, foggy-headedness, and impaired concentration . A new study published in The Journal of Clinical Psychiatry supports the premise that increased inflammation may play a role in depression. The large study examined data from 14,275 people who were interviewedbetween 2007 and 2012usingthe Patient Health Questionnaire (PHQ-9) to screen for depression and had blood samplesdrawn. They found that people who had depression had 46% higher levels of C-reactive protein (CRP), a marker of inflammatory disease, in their blood samples.
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